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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf5333b43f6a7c3316f3749543952cc4e7e19cfd41eac4aa2ab08888384c4a7' 
  AND token = 'vCVmp6Vu17aLLo2iZYaDX+ZX3tdzQCWsG7e4qNs3QuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}