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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aea83d7da3b65afcddfd10c0a607233741ac67df7d7dc3d1cdf632d44be8e208' 
  AND token = '6vTUMCe4wkbV9rhVq1zSJ9PxzB5HHw/I9RHhS7Jwegs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}