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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0eb8d9e1c9be4b25f26ea5dafda9f1f2bbf1d9a90da5e5410f92bc7ddddea5' 
  AND token = 'MCBvv14awaKcMVFQa7hifYir9Az9Z1UjbwgiEtNiKks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}