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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c861b0b5700a59f0120b4abb2c435894412807263ef9c7243ee3094b25453b00' 
  AND token = 'HpjrB9RMB2BvCzM3tnfyZiyFqBgovrnWlnEqMYec0fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}