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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00cb171c039080b049f79d3209ea80073d21d342532f10252e3f3ff51e80601' 
  AND token = 'Gy67dd6fqFJ3fZ40sHDpxJDu9/hceYe13Y0WPt60Kbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}