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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc80fe4d060b53622054357c9bd59dac2f83371b790209d213c8ffde5c0cb43a' 
  AND token = '0JBbDkqsDUl+MwMSAjVnxn5jjswDowOOB7A+8Y8IsOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}