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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '947df529cece1681210e9e9c591f2681f0d8399aac9cd7f56d30befb57b6ee5e' 
  AND token = 'uM9JU3eL1q2kjT3BilvhxMvtYUoNFcYIpfo2DCObzDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}