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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522ae9172e3fef61208cf6aec6f347311d8a6b085a9d73d5a6d437aa497615d3' 
  AND token = 'PLPbIGbQxWdV8FraeLEnQ6TAuUmW142SJ5Sd6C1N5ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}