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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f65487a1dd9dc4caf01bcf6f618afd73131fae4221d09979501ce4a221f6194' 
  AND token = '9X07xQyrq4i/0GR+S8QEj6sk7EQUxkWfbgZxUnh199A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}