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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa1ed5b4d0cd1b2a2301c01952e2c2f3e3fe80478664dfea1133bddea4ec1585' 
  AND token = 'GceTtFcDIQiTEb7uxBOtBFeU6lz5jI5OtK37tGarTQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}