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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d136c863673fc0835da836e833201692e518019a8009e96bee391e778cf2230' 
  AND token = 'YgYe1PPkpZU1tp5RaTruxsu94hQdsvnZq/yAocL4oMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}