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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c108aecb836fb6425198ce301d065ce9cb347efa007d2e8b064b12ef2abcecad' 
  AND token = 'I+0tI6ELurWaeAvtWxlHd8L/0dVEqMEvV4p8dM0Re5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}