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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ee38d603fc5622a4ebc23e05485cbb3e57ba7261dc85114adbde9feec777a7' 
  AND token = '4thc+aLruuol45k9XQmRzgp0BJLHqKkdmfqbbFD7Erc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}