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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ce89ccd729920bef41bdf0d37bb75db35e23b9d00a258bca6e0c169782e69e' 
  AND token = 'MDzTz/YgiyIYD7xaM0sa9O+FnIS73/iAT3uwt43rRm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}