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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcf0a166f4468bf834a3521bb94b7232545a4de950ef53fc7e00c8a3fac80dc3' 
  AND token = 'L99D0Pzlt0pvChcbPvCjHRA7DpZB1/3fxXTe3e9F8rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}