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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fbe26068d9e957e988d359ebd55dd650fb82c418ddaff91b05aae481d8b914a' 
  AND token = 'H9k1KBVR7uUZJ1vQxObHhBAh4LbJwfC20++7T3oMFK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}