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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f518bcd78c36b34dff907403f47df0e43e40b1bcc9579960e7f0148b2e8391c' 
  AND token = 'siA1l1aAo5TdH3Ox/ioX6pTG2YT+W+x0fVK0xa09srg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}