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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be40d76f26a6de7a3c6fbc6ab91e13e656c3d8cb5e5a9a015027cb597b5a34f' 
  AND token = 'Ro+WMne8+nZueMolNlvihbzvII05ONmi3sOc0eks1ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}