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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6224a866e384499d37c3322ff321eab60dcd7585f97965a9338e5ce451ad13ab' 
  AND token = 'flBZIzpT0Cp/dzmnV+4aD0QMP09gN17d7fXg9T8ivOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}