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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b77c8c5c89e1a814cc48b45d655c7147d1ffa0c0e5f092cb2f839f9f1b6d77a' 
  AND token = 'izXXdoT1qWxj8naHEgD0CkZ7cXuXJxV5+TVgYLf5Yxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}