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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64ade341a9d52332485e303de36c9942a83925480df0c2dbabd2863244f152a' 
  AND token = 'oWuMRUtU3I21igXxIblSqg4pIHc09YZgUJ+fgNbPtRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}