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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bdcab0e45ed55f4202e5fe268a5e408064c98874c5d97540c6d3aa29629b651' 
  AND token = 'z7RUqdxTaRjHYfTEA0z8RDwChHGalAb6a5ig8RKTqqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}