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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9ced63da04296c955d1d275b83a7a09f044d402b7f24f3008806be1cb4e591' 
  AND token = 'hkQHW5nr7CsnfXp5nVQf3aZFh8t+pMUAVvRcQaSX+0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}