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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3977e84adcbd9b9b818af3f19706e9787a45835852c14138ad2dfc96c9594112' 
  AND token = 'dce6RExaHF6K8A/KgMS421Y7IcPs4PqMD7PnVjLtvW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}