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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17875208c5053bc1983dd244aeae002ac390ab3f7e4fe810c79f5c1f3029d399' 
  AND token = 'P5aa4j3TWyjA18gZ1dOfacxETYObXpZ/GYLhSj+6Qo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}