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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44af31662135a834f1588dd03b6ec12133df9e18ea9b7c9f73bf0ad3897fa759' 
  AND token = 'no9eBNRsYnK7IB+zB7llhvyecykDYvTBabkH60zuBq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}