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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b2fc8b91274c44c221bf625a4c5683253fec540efe9765ccb2425dcf97ec30' 
  AND token = '+6gSzPTkJZEUgX+T+geTe96HP87/HE3Z+Ty1+Meps3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}