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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f99db5938ceb409380e465c4be45e3f814e221356a745c152184b960e048ab26' 
  AND token = 'w4OD8Rzub6gsoHMe8mVqhDUatIpCBQ+Baoy8wBLk4rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}