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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7072a0cd1b4ba24aa7120e19409c465cb0bafca0d985b53d8d21ae9f0f849131' 
  AND token = '7s4AEBfjpYhqGwfKykQQQM1NKgW+vgDxF5ol2kqIwfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}