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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765ad3c264398872b2cd689f13a71fd1a0e6f496e828759ee3eaeeb699a7fe8c' 
  AND token = 'uEkYCpU4egzt536eLoPV3leG8eS0IPl96gymwgnmDDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}