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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f54a548c0bd07dce1df1dd2fdb97e5e1e407dfb1a128307731d0ee488602f48' 
  AND token = '+/WvaiMjQhMYdnO1b1rCIuEop2iaZCZ+drSMJ8am7IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}