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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd1be9c5017baef6381f8b3279fba388c7ae67b2a1389a1dd3a96e0200312c0a' 
  AND token = 'ZbqV3nMCzC86+3gFLFxqNmI0cBGWpEX7Cj4xlFKx79s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}