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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a19fe1c6b003d47e9efdd7865c7b767d253fa069b3c151dd9a807067ffc849' 
  AND token = 'mlUnH1lYdUxhFt3qepiw36AFJXaGKAvADXRmO9JI63g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}