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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dd9db572cb55e851492f77bb9b3680210393a3731d687fcfa1df2eb805c0713' 
  AND token = '5r/40Ks+2Z93tpPRRq132+sDfEbP/YUcGPfSYRS5sFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}