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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456dae1b30468501e864ddf22354803e4f7336a6fe7aa464e26add2de6ca1168' 
  AND token = 'QZpnvfhB3oRe5z8RCrlcBeA4iOaEwaLofbnOuauUN/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}