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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05553ccab098e4f0517fe02e64267690edf5e26bf16cf72112c5e8a456a9ad3' 
  AND token = 'wI0g5a/Ya0gILxbmPErMRP+HiORlmkEDVQ5qyz8urtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}