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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b27f91523477cc0bae5ef6653703e79b07b7403ca3eca196cd6be51c62410f2' 
  AND token = 'jucoa7UTMOMh1T4nVeeJy5c5zbl/pDR6HWT4s7BseTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}