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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c489c808a366d4ed754b21b4279268cabda707686f1c1e2851ba703c464d4b' 
  AND token = 'rp+H+E4OQIm0sJuYH+rDrOdYNqNDv3VEyTbGzT5PdNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}