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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a10962cfe1ff651766b9e32e271c78d64d681e90151aa2b2fdf14b6f9da863e' 
  AND token = '9f1Wp1NOVw5l4SPWokW1yFKsbMYXKriuqjoWlNR2UQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}