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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19665467da07b7e15adc40a8b2065b8aa4294614f0c81105c7f648c3275519c3' 
  AND token = 'z8qZwyaeS9P2AXYFi5QJWwV2b45DVn/uFHrtIwE8zZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}