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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ddc3f209bc3602db391b2ac3577f0d0c09a6839f228056185c498a3ff5fa60' 
  AND token = 'PRNmieQ6a27350zKUvPDsSEF+ndeIh1PS+eAkCElELo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}