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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d26617077c6f7f1a1750724b488fa6603dcb2d1cb44f9c81a686c7bb401a03' 
  AND token = '4FrenuorBmnvZ1YVjdH9hUneoNHzeafE6Wz4FdzEiLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}