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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e4f17ee6cc303176ae6aee2f4545fb8fc279ae9d0ae9ff6463f72b902fcd943' 
  AND token = 'Z3skbeavDhnivhL936r1xxZBNQ3DVe0nExXKnT5x3dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}