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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10bc7bd220bd11ba6d043f75f6ea531fd9a360db44021ce4bc96908ac261cddf' 
  AND token = 'xAk42lWFhijjXGelB93fR2FJYQQq5qCP+0BY52+mGtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}