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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577dcf8c62a25d8eac0b9170c8b40995d4f9d5d8f38028fa2eb5c4fddeb2b7b5' 
  AND token = 'u7RIjwl+YGM8eRbaCmfHkbHt5yygY0n0tbw0/YzvlJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}