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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70c0135863b5b8bf43cb1433bd25d63d9f6554f25dae3e8054cc43eb23d14df7' 
  AND token = '2xIkvQh1+uJK77Cm+B1RQAToDTnVqV63Qu9LS8XIeq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}