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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb69aa5c938108119fb8a98c5055ca8e14a1b2da019109a93faae93449b41f68' 
  AND token = '1aPMi7tG9Id0iU+reA2xtIctPYUIEHESFFuY73brHGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}