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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7292e7a0d25b9e4766c2d0463b37f1cec9de8b6f710f5130cb1746a20d8e9f4a' 
  AND token = 'WlnbhB0K6sPrnlhR3WcgHvn2HZ5ldhTGkp12N2YkcBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}