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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '043984819a210c12fc86105a776bce1ba1fc8144b3f4b9376f20ed19a49d16ed' 
  AND token = 'UoDo1sOko/w/2h3Mr/5A7eEdftL3zGPTJL8tW2tyQ20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}