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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f373785ffab5334c6a30ac7a5d2cd4d0949b720e059e1c4d50253efdc770fa6' 
  AND token = 'rKwg0kJyK6OunOyziEGRRYnyX7Ps6bZZyn2H1YLI3Y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}